Another study suggested that for effective immunosuppressive treatment in dogs, the dosage of
ciclosporin A requires adjustments in the course of therapy, guided by serum values and the animals age (MORINI et al., 2008).
Ciclosporin administration during pregnancy induces ultrastructural changes on pancreatic beta-cells of newborn rats.
Patients with mild disease usually require only topical treatment however those with moderate to severe disease generally require phototherapy,
ciclosporin, methotrexate and acitretin.
Depending on the associated systemic disease, it is not infrequent the need to scale immunosuppressive therapy with cytotoxic (cyclophosphamide) or immunomodulating agents (methotrexate or
ciclosporin), in order to halt the systemic and ocular inflammatory process.
ND: not described; gender: M(ale)/F(emale); CS: corticosteroid; CsA:
ciclosporin; AZA: azathioprine; CPA: cyclophosphamide; FFP: fresh frozen plasma; PE: plasma exchange; PP: plasmapheresis; BA: bypassing agents, for example, FEIBA (Factor Eight Inhibitor Bypassing Activity) or rFVII (recombinant Factor Seven); MTX: methotrexate; *: our case report.
Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis.
Ciclosporin population pharmacokinetics and Bayesian estimation in thoracic transplant recipients.
Open trial of
ciclosporin treatment for Stevens- Johnson syndrome and toxic epidermal necrolysis.
"In my 10 years dialysing at home a new drug called
ciclosporin was discovered and I believe this has helped my kidney survive along with the good care of local doctors and the renal team at James Cook University Hospital, Dr Kenward, Dr Patterson and now Dr Wroe."
Methotrexate,
ciclosporin and acitretin are commonly used medications for managing psoriasis.