cholecystokinin

[ko″le-sis″to-ki´nin]

a polypeptide hormone secreted in the small intestine, which stimulates gallbladder contraction and secretion of pancreatic enzymes.

cho·le·cys·to·ki·nin (CCK),

(kō'lē-sis-tō-kī'nin), [MIM*118440]

A polypeptide hormone (the human peptide has 33 residues) liberated by the upper intestinal mucosa on contact with gastric contents; stimulates contraction of the gallbladder and secretion of pancreatic juice.

Synonym(s): CCK-pancreozymin, pancreozymin

Farlex Partner Medical Dictionary © Farlex 2012

cholecystokinin

(kō′lĭ-sĭs′tə-kī′nĭn)

n. Abbr. CCK

A hormone produced principally by the small intestine in response to the presence of fats, causing contraction of the gallbladder, release of bile, and secretion of pancreatic digestive enzymes. Also called pancreozymin.

cho·le·cys·to·ki·nin

(CCK) (kō'lĕ-sis'tō-kī'nin)

A polypeptide hormone liberated by the upper intestinal mucosa on contact with gastric contents; stimulates contraction of the gallbladder and secretion of pancreatic juice.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cholecystokinin

A HORMONE released into the blood from the lining of the duodenum when fat and acid are present. It causes the gallbladder to contract and the sphincter of Oddi to relax, so sending bile into the duodenum to emulsify the fat, and stimulates the pancreas to secrete fat- and protein-splitting enzymes. The hormone also inhibits the motility of the stomach and the secretion of gastric acid.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

cholecystokinin (CCK) (formerly pancreozymin)

) a single hormone secreted by the wall of the duodenum in mammals when food enters the small intestine. CCK causes contraction of the gallbladder muscle, resulting in bile being pumped into the duodenum via the bile duct, and stimulates the pancreas to secrete pancreatic juice containing large quantities of digestive enzymes, which enter the duodenum via the lower part of the bile duct. CCK causes VASODILATION of the intestinal blood vessels.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Mentioned in

References in periodicals archive

Cholecystokinin and peptide Y in yellowtail (Seriola quinqueradiata): Molecular cloning, real-time quantitative RT-PCR, and response to feeding and fasting.

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

Excessive drinking of alcohol and intake of high fat foods cause cholecystokinin receptor (CCKR) signaling pathways to induce intra-acinar activation of trypsinogen.

Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders

Potato protease inhibitors inhibit food intake and increase circulating cholecystokinin levels by a trypsin-dependent mechanism.

Anti-tryptic activity in seed and food product of chia (Salvia hispanica L.)/Atividade antitriptica em semente e produto alimenticio de chia (Salvia hispanica L.)

Delayed biliary-to-bowel transit in cholescintigraphy after cholecystokinin treatment.

Applied hepatobiliary scintigraphy in chronic gallbladder diseases

Also, for both patients, a cholecystokinin infusion administered to calculate EF reproduced their pain.

Biliary pain, no gallstones--remove the gallbladder, anyway? As these 2 cases show, cholecystectomy may be helpful for such patients, even those with a high ejection fraction

Similarly, receptors of other neuropeptides like somatostatin, neuropeptide Y, galanin, dynorphin, enkephalin, substance P, cholecystokinin, vasoactive intestinal polypeptide, hormones such as ghrelin, angiotensins, corticotropin-releasing hormone, adrenocorticotropin, thyrotropin-releasing hormone, oxytocin, and vasopressin involved in epilepsy [100].

Transendothelial transport and its role in therapeutics

Mechanisms of protein that act on food intake include slowing gastric emptying and direct or indirect stimulation of gastrointestinal hormones such as cholecystokinin and glucagon like peptide-1 [13].

The effects of soy bean flour enriched bread intake on anthropometric indices and blood pressure in type 2 diabetic women: a crossover randomized controlled clinical trial

Sulfated cholecystokinin octapeptide (CCK-8), lipopolysaccharide (LPS; Escherichia coli serotype O111:B4), aminoguanidine (AG), dexamethasone (DEX), pyrrolidine dithiocarbamate (pDTC), SQ-22,536, H-89, and forskolin were obtained from Sigma-Aldrich (St.

Cholecystokinin inhibits inducible nitric oxide synthase expression by lipopolysaccharide-stimulated peritoneal macrophages

The related release and detection of nutrients in the small intestine was confirmed by blood serum levels of the hormone cholecystokinin.

Optimize food structure for enhanced satiety

What is known is that excessive concentrations of cholecystokinin (CCK) and peptide YY occur in critical illness, and that high levels are correlated with feed intolerance and slow gastric emptying.

Gut dysfunction in the critically ill--mechanisms and clinical implications