chilblain lupus type 2
chilblain lupus type 2
A rare cutaneous form (OMIM:614415) of lupus erythematosus, which presents with painful bluish-red papular or nodular lesions of acral skin, precipitated by cold and wet exposure at temperatures < 10º.
Molecular pathology
Defects in SAMHD1, which encodes a putative nuclease involved in the innate immune response, cause chilblain lupus type 2.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Copyright © 2003-2025 Farlex, Inc
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.