Mor·gan

(mōr'găn),

Harry de R., British physician, 1863-1931. See: Morgan bacillus.

mor·gan (M),

(mōr'găn),

The standard unit of genetic distance on the genetic map: the distance between two loci such that on average one crossing over will occur per meiosis; for working purposes, the centimorgan (0.01 M) is used.

[T.H. Morgan, U.S. geneticist, 1866-1945]

Farlex Partner Medical Dictionary © Farlex 2012

map unit

An arbitrary unit for the distance between genes, usually derived from the percentage of recombination, but also defined by the time at which the gene is transferred during conjugation. One map unit corresponds to a recombination frequency of 1%.

mor·gan

(mōr'găn)

[T.H. Morgan, U.S. geneticist, 1866-1945]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

centimorgan

A unit of distance between two genes on a chromosome, representing a 1 per cent probability of recombination in a single meiotic event. Named after Thomas Hunt Morgan (1866–1945) the American Nobel-prizewinning geneticist often described as the father of modern genetics.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

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References in periodicals archive

Again, records are scarce, and without a historical trail to follow, Eve asked Trotsky's great-granddaughter to test her DNA so we can compare centimorgans. But these are tales for another day.

Jewish genes as time machines: a lonely Jew reassembles her vanished family through a combination of genealogical sleuthing, genetic testing and cousin-fishing

A statistically significant (P < 0.0001) association was also detected between SCN resistance and the genetic region that spans four AFLP and two SSR markers from centimorgan position 30.2 ([E.sub.AGC][M.sub.AAG]176) to at least centimorgan position 48.7 (Satt472) within population A81-1-2 (Fig.

Localization of two loci that confer resistance to soybean cyst nematode from Glycine soja PI 468916

Map units in centimorgans (cM) were derived from the Kosambi function (Kosambi, 1944), and the map was drawn by MapChart 2.1 (Voorrips, 2002).

Identification of male-specific AFLP markers in dioecious Texas bluegrass

Abbreviations: AIL, advanced intercross line; cM, centimorgan; G x E, genotype by environment; ID, inflorescence density; IM, interval mapping; MAS, marker-assisted selection; MQM, multiple-QTL mapping: QTL, quantitative trait locus; SY, seed yield; TSW, thousand-seed weight: YI, yield per inflorescence.

A QTL analysis of white clover seed production

The Kosambi mapping function was used to compute the map distances in centimorgans (cM) from the recombination fractions.

Molecular mapping of nuclear male sterility genes in sunflower

A linkage map was constructed using JoinMap (Stam, 1993) by placing 33 out of 350 polymorphic RAPD markers on 10 partial LGs for a total length of 183 centimorgans (cM).

Identification of quantitative trait loci conditioning resistance to Fusarium root rot in common bean

([section]) This position is based on the composite integrated genetic linkage map of the soybean; cM = Map distance in centimorgans. ([paragraph]) Log of odds ratio.

Quantitative trait loci for seed protein and oil concentration, and seed size in soybean

The Kosambi function was used to obtain centimorgan (cM) values.

Inheritance and genetic mapping of resistance to Rhizoctonia root and hypocotyl rot in soybean

The uniRec method was, however, effective at equalizing the number of recombinations per centimorgan observed across intervals of different lengths (Fig.

Selective phenotyping to accurately map quantitative trait loci

(c) Marshfield sex-averaged map location as measured in Kosambi centimorgans from the top of the short arm of the chromosome (Marshfield website).

CURRENT UNDERSTANDING OF THE GENETIC BASIS OF READING AND SPELLING DISABILITY

This represents a substantial improvement over standard mapping strategies, which yield only statistically based confidence intervals on the order of 10 to 30 centiMorgans (cM), corresponding to about 20 to 50 Mb in mice (Glazier et al.

Interval-specific congenic animals for high-resolution quantitative trait loci mapping

The combined genome scan data included 458 markers that were typed in 2 or more scans, which were included separately on the genetic map for the scan, separated by a very small distance [0.001 centimorgans (cM)].

Butyrylcholinesterase: association with the metabolic syndrome and identification of 2 gene loci affecting activity