Medical

cardiac troponin I

Also found in: Acronyms.

cardiac troponin I

A regulatory protein that has been found to be a sensitive marker for heart damage from heart attack (myocardial infarction) occurring during surgery, a time when the detection of a heart attack may be clinically difficult. Blood levels of this protein are measured prior to surgery and at intervals of a few hours afterwards. A rise is strongly suggestive of a myocardial infarction. The method does not replace the conventional procedures of creatine kinase measurement, ELECTROCARDIOGRAPHY and ECHOCARDIOGRAPHY.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive
Measurement of cardiac troponin I in serum with a new high-sensitivity assay in a large multi-ethnic Asian cohort and the impact of gender.
Impact of high-sensitivity troponin I testing with sex-specific cutoffs on the diagnosis of acute myocardial infarction
Matrix and bilirubin interference for high-sensitivity cardiac troponin I. Clin Chim Acta 2015; 442:49-51.
Acceptable analytical variation may exceed high-sensitivity cardiac troponin I cutoffs in early rule-out and rule-in acute myocardial infarction algorithms
High sensitivity cardiac troponin I and T assays for predicting death in a hemodialysis population.
Prognostic value of serial changes in high-sensitivity cardiac troponin I and T over 3 months using reference change values in hemodialysis patients
Cardiac troponin is the standard biomarker for detection of myocardial injury.
Serial changes in high-sensitivity cardiac troponin, N-terminal Pro-B-type natriuretic peptide, and heart fatty acid binding protein during exercise echocardiography in patients with suspected angina pectoris and normal resting left ventricular function
Normal plasma levels of cardiac troponin I measured by the high-sensitivity cardiac troponin I access prototype assay and the impact on the diagnosis of myocardial ischemia.
Comparison of cardiac troponins I and T measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy
Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events.
Weekly and 90-minute biological variations in cardiac troponin T and cardiac troponin I in hemodialysis patients and healthy controls
Comparison of myoglobin, creatine kinase-MB, and cardiac troponin I for diagnosis of acute myocardial infarction.
COMPARISON OF TROPONIN I WITH CK-MB AND ECG FOR PREDICTING CLINICALLY SIGNIFICANT MYOCARDIAL INJURY AFTER CORONARY ARTERY BYPASS GRAFTING
The complete pharmacokinetic profile of serum cardiac troponin I in the rat and the dog.
Cardiac Troponin - A Cardiac Biomarker for Point of Care Testing in Acute Heart Failure Syndrome in Canines
Cardiac troponin is a member of a complex group of proteins that modulate the calcium-mediated interaction between actin and myosin within the cardiac myocytes.
Multiple admissions to the coronary care unit due to falsely elevated cardiac troponin
[2] Nonstandard abbreviations: cTnT, cardiac troponin T; cTnI, cardiac troponin I; AMI, acute myocardial infarction; ACS, acute coronary syndromes; TnC, troponin C; HAMA, human antimouse antibodies.
Cardiac Troponins: Molecules of Many Surprises
Indeed, proteolysis will produce various cardiac troponin I molecules with varying degrees of stability hence it is not unreasonable to assume that unpredictable interactions between these molecules and the antibodies in the assay can occur [12].
Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: an experimental study
Anecdotal experience in the laboratory was that clinicians were continuing to order cardiac troponin I (cTnI) together with the CK-MB isoform in cases of suspected ACS.
Clinicians ignore best practice guidelines: prospective audit of cardiac injury marker ordering in patients with chest pain
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