hypertrophy
[hi-per´tro-fe] increase in volume of a tissue or organ produced entirely by enlargement of existing cells. See also
hyperplasia and
proliferation. adj.,
adj hypertro´phic.
asymmetrical septal hypertrophy benign prostatic hypertrophy (BPH) age-associated enlargement of the prostate resulting from proliferation of glandular and stromal elements, beginning generally in the fifth decade of life; it may cause urethral compression and obstruction. Called also
benign prostatic hyperplasia and
nodular hyperplasia of the prostate.
cardiac hypertrophy enlargement of myocardial cells and hyperplasia of nonmuscular cardiac components due to pressure and volume overload and sometimes to neurohumoral factors.
compensatory hypertrophy that which results from an increased workload due to some physical defect, such as in an organ where one part is defective, or in one kidney when the other is absent or nonfunctional.
functional hypertrophy hypertrophy of an organ or part caused by its increased activity.
ventricular hypertrophy hypertrophy of the myocardium of a ventricle, due to chronic pressure overload; it is manifest electrocardiographically by increased QRS complex voltage, frequently accompanied by repolarization changes.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.