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cardiac hypertrophy

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hypertrophy

 [hi-per´tro-fe]
increase in volume of a tissue or organ produced entirely by enlargement of existing cells. See also hyperplasia and proliferation. adj., adj hypertro´phic.
asymmetrical septal hypertrophy
2. the term is sometimes limited to cases of hypertrophic cardiomyopathy in which the hypertrophy is localized to the interventricular septum. See also hypertrophic obstructive cardiomyopathy.
benign prostatic hypertrophy (BPH) age-associated enlargement of the prostate resulting from proliferation of glandular and stromal elements, beginning generally in the fifth decade of life; it may cause urethral compression and obstruction. Called also benign prostatic hyperplasia and nodular hyperplasia of the prostate.
cardiac hypertrophy enlargement of myocardial cells and hyperplasia of nonmuscular cardiac components due to pressure and volume overload and sometimes to neurohumoral factors.
compensatory hypertrophy that which results from an increased workload due to some physical defect, such as in an organ where one part is defective, or in one kidney when the other is absent or nonfunctional.
functional hypertrophy hypertrophy of an organ or part caused by its increased activity.
ventricular hypertrophy hypertrophy of the myocardium of a ventricle, due to chronic pressure overload; it is manifest electrocardiographically by increased QRS complex voltage, frequently accompanied by repolarization changes.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cardiac hypertrophy

Compensatory enlargement of the heart, which may be physiologic, as occurs in athletes, or pathological, due to underlying cardiac disease—e.g., congestive heart failure, valve disease, hypertension.

Types
• Pressure load hypertrophy—e.g., aortic valve stenosis; the left ventricular wall is thickened to 2 cm or more.
• Volume load hypertrophy—e.g., aortic valve regurgitation; the left ventricular cavity diameter is greatly increased; the wall is unchanged.

Determinants, left ventricular mass
Total body size, amount of regular physical exercise, blood pressure.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

cardiac hypertrophy

Cardiac enlargement Compensatory enlargement of the heart, which may be pathologic, due to underlying cardiac disease–eg, CHF, valve disease, HTN, or physiologic, as in athletes. See Athlete's heart syndrome, Congestive heart failure.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
In the present study, we aimed to investigate the function of miR-24 in cardiac hypertrophy by establishing a transverse aortic constriction (TAC) rat model, and miR-24 overexpressing in neonatal rat cardiac myocytes (NRCMs).
Cardiac hypertrophy is an early consequence of maternal diet-induced obesity that is associated with impaired systolic and diastolic function, impaired ventricular contractility, and reduced myocardial compliance in young-adult offspring of obese dams [133].
Lv et al., "LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII," Oncotarget, vol.
In summary, the Hippo pathway which primarily functions through the YAP effector protein, mediates cardiac hypertrophy and apoptosis, although it seems that whether YAP could induce hypertrophy depends on different backgrounds.
(29) The cardiac effects of hibiscus, however, are less well known; but in an animal model, it reversed cardiac hypertrophy associated with hypertension.
Danon disease is a rare genetic disorder presenting with progressive cardiac hypertrophy, Wolf-Parkinson-White (WPW) syndrome, skeletal myopathy, and mild intellectual disability [1, 2].
Cardiac hypertrophy and arterial alteration in end-stage renal disease: hemodynamic factors.
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