car·bo·gen

(kar'bō-jen),

A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.

[carbon dioxide + oxygen]

Farlex Partner Medical Dictionary © Farlex 2012

carbogen

An inhalant of O2 and CO2. Meduna’s original formulation called for 30% CO2 and 70% O2, but the term has been genericised and now refers to any CO2 concentration from 1.5% to 50%. The brain responds to increased CO by increasing breathing and heart rates.

Fringe psychiatry
Carbogen was used in psychedelic therapy in combination with LSD, psilocybin, DMT and 2C-B to ensure a smoother, more profound experience; hallucinogenic psychotherapy remains outside of mainstream medicine.

Oncology
The carbogen used in oncology is a mixture of 95% O2 and 5% CO2 and inhaled as a therapeutic adjunct, based on the premise that because tumours thrive in hypoxic conditions, increasing tumour oxygenation during radiotherapy or chemotherapy should increase tumour susceptibility to the therapy. It is considered investigational and is not reimbursed by BlueCross and BlueShield.

Psychiatric history
Meduna used carbogen to assess whether to manage patients with psychotherapeutics; those who reacted poorly to the altered state of consciousness induced by carbogen were de-selected for psychotherapeutic drugs, given the concern that they might evoke a similar response.

car·bo·gen

(kahr'bō-jen)

A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.

[carbon dioxide + oxygen]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

References in periodicals archive

This solution was continuously oxygenated with carbogen gas (95% [O.sub.2] + 5% C[O.sub.2]) throughout the experiment starting at least 30 minutes prior to obtaining the brain slices.

Biophysical Properties of ERG Channels in Octopus Neurons of Ventral Cochlear Nucleus

Johnson held positions as director for the high potency division of Dishman Group's Carbogen Amcis operation, headquartered in Basel and as business manager for the strategic marketing of the oncology portfolio of Italy's UQUIFA.

The ADC Market is Fast Evolving: Applications of ADCs are widening and improvements in the manufacturing process meet industry requirements

The increase in blood flow in nonsmokers due to carbogen respiration was found in comparison to the relatively stable blood flow in smokers.

The Effect of Smoking on Macular, Choroidal, and Retina Nerve Fiber Layer Thickness

9 and glucose 11.1; pH 7.5 at 37 [degrees]C) and constantly aerated by carbogen (95% [O.sub.2] - 5 % C[O.sub.2]), while control samples were exposed to Tyrode alone (n = 3-5 per group) at same conditions.

Extracto metanolico de Rhinella schneideri (Anura: Bufonidae) causa cambios ultraestructurales en las terminaciones nerviosas de preparaciones de nervio frenico de raton

The skull cavities were washed with synthetic interstitial fluid (SIF) containing (in mM): 120 NaCl, 5 KCl, 2 Ca[Cl.sub.2], 1 Mg[Cl.sub.2], 11 glucose, 1 NaHP[O.sub.4], 24 NaHC[O.sub.3], continuously gassed with carbogen (95% [O.sub.2] and 5% [CO.sub.2]), equilibrating the solution at pH 7.4 at room temperature.

Mast Cell Degranulation Mediates Compound 48/80-Induced Meningeal Vasodilatation Underlying Migraine Pain/Mast Hucre Degranulasyonu Compound 48/80 ile Tetiklenmis Migren Agrisinin Altinda Yatan Meningeal Vazodilatasyona Aracilik Ediyor

Carbogen therapy is one of them which acts by inhalation, increases arterial oxygen saturation and maximises oxygen supply to the inner ear.

THERAPEUTIC EFFECTS OF CARBOGEN THERAPY IN SUDDEN SENSORINEURAL HEARING LOSS

The most frequently used gas is carbogen (95% [O.sub.2] and 5% C[O.sub.2]) as described in Kietzmann's model (Kietzmann et al., 1993).

Extracorporeal Perfusion of Isolated Organs of Large Animals--Bridging the Gap Between In Vitro and In Vivo Studies

The jejunum was cut into equal segments, flushed with normal saline to remove the contents, and then immersed in ice-cold Krebs solution that was pregassed with carbogen. Each segment was inverted by gently pushing a notched glass rod through the whole length of the intestine and then filled with 1 ml of Krebs solution.

Intestinal Permeability of Artesunate-Loaded Solid Lipid Nanoparticles Using the Everted Gut Method

Full urinary bladder and ileum were carefully removed from the abdomen, then placed in cold Kreb's solution (118 mM NaCl, 4.7 mM KCl, 25 mM NaHC[O.sub.3], 1.15 mM Na[H.sub.2]P[O.sub.4], 2.5 mM Ca[Cl.sub.2], 1.1 mM Mg[Cl.sub.2], and 5.6 mM glucose), equilibrated with a carbogen mixture (95% [O.sub.2], 5% C[O.sub.2]) [32].

Discovery of Novel Caeridins from the Skin Secretion of the Australian White's Tree Frog, Litoria caerulea

Kronenberg, "Steroids, carbogen or placebo for sudden hearing loss: a prospective doubleblind study," European Archives of Oto-Rhino-Laryngology, vol.

Manipulation of Auditory Inputs as Rehabilitation Therapy for Maladaptive Auditory Cortical Reorganization