Medical

calpain

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calpain

(kăl′pān′)
n.
A proteolytic enzyme regulated by the concentration of calcium ions.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
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The research into the activity of tissue enzymes were also assessed - with regards to cathepsins and calpains - in the muscular fiber of red deer meat.
Accumulation of Ca2+ will activate calpain 3 kinase that in turn cause degradation of myofibrils.
CaSR and calpain contribute to the ischemia reperfusion injury of spinal cord.
Degradation of [alpha]-spectrin by calpain is one of the first events required for receptor internalization.
Synaptojanin-I is predominantly distributed in nerve terminals and is extremely sensitive to calpain digestion [57]; therefore, it has been taken as a novel target for degradomic calpain [51].
review the current literature on the ischemia reperfusion injury following myocardial infarction, highlighting the relevance of a calpain system, oxidative and NO-linked pathways, and ventricular remodelling discussing the evidences from a medico-legal standpoint to better understand sudden deaths following myocardial infarction [11,12].
Also they have been evaluated as cardiovascular agents calpain inhibitors [15] and calcium antagonists [16].
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