burned-out phase

burned-out phase

A desirable end-stage of polycythemia vera, where hyperproduction of erythrocytes settles down and much of the bone marrow is replaced by reactive fibroblasts, which produce the collagen typical of myelofibrosis.

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burned-out phase

'Spent' phase Hematology A desirable end-stage of polycythemia vera, where hyperproduction of erythrocytes settles down and much of the BM is replaced by reactive fibroblasts which produce the collagen typical of myelofibrosis

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.