Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro .
On the basis of type, the global bone morphogenetic protein market is sub divided into recombinant
bone morphogenetic protein-7 (rhBMP-7) and recombinant bone morphogenetic protein-2 (rhBMP-2).
Mariel Therapeutics is a clinical stage biopharmaceutical company focused on the clinical application of
Bone Morphogenetic Protein-7 (BMP-7) in osteoarthritis, chronic kidney disease, and Alport's Syndrome.
Regeneration of articular cartilage chondral defects by osteogenic protein-1 (
bone morphogenetic protein-7) in sheep.
Harris et al., "Expression of
bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney," The American Journal of Physiology--Renal Physiology, vol.
Bone morphogenetic protein-7 (BMP-7; also called osteogenic protein-1), is a member of the Transforming Growth Factor b (TGF-b) superfamily, which was originally isolated from bone (1-3).
M2 EQUITYBITES-July 8, 2014-Mariel Therapeutics to acquire Stryker's
Bone Morphogenetic Protein-7 assets
M2 PHARMA-July 8, 2014-Mariel Therapeutics to acquire Stryker's
Bone Morphogenetic Protein-7 assets
8 July 2014 - US clinical stage biopharmaceutical company Mariel Therapeutics Inc said it had agreed to buy medical technology firm Stryker Corp's (NYSE:SYK)
bone morphogenetic protein-7 (BMP-7) assets for the potential treatment of osteoarthritis (OA), chronic kidney disease (CKD) and other organ fibrosis conditions, lupus, and obesity.
Recombinant transforming growth factors-[beta]1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (
Bone Morphogenetic Protein-7) to initiate rapid bone formation.
Paul Krebsbach, DDS and colleagues from the University of Michigan School of Dentistry in Ann Arbor used an adenovirus vector engineered to express
bone morphogenetic protein-7 (BMP-7) to transduce human gingival or rat dermal fibroblasts.