Medical

bone marrow ablation

bone marrow ablation

Radio- or chemotherapy-induced destruction of bone marrow harbouring (or potentially harbouring) malignant cells, which remain after the administration of systemic chemotherapy. The patient’s own stem cells are used to reconstitute the marrow.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

bone marrow ablation

Oncology The destruction of BM with radiation or drugs
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Additional AEs observed in clinical studies were consistent with the known side effects of HSC and bone marrow ablation with busulfan including SAEs of veno-occlusive disease.
bluebird bio Receives Positive Opinion from CHMP for Zynteglo Gene Therapy for Patients 12 Years and Older with Transfusion-Dependent I[superscript two]-Thalassemia Who Do Not Have I[superscript two]0/I[superscript two]0 Genotype
In this procedure healthy blood stem cells home in to the bone marrow to regenerate the blood system of cancer patients following bone marrow ablation through chemotherapy or radiation.
Engineered cells could usher in programmable cell therapies
However, in a leukemia patient whose chemotherapy results in successful bone marrow ablation, the bone marrow would be dark on an FLT PET scan.
In patients with acute myelogenous leukemia (AML) undergoing a standard 7-day course of chemotherapy, positron emission tomography (PET) using the radiotracer fluoro-L-thymidine (FLT)
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