These often include
beta-lactams, a class of antibiotics that include penicillin and a host of other structurally related compounds.
The proposed Phase 3 study proposes to evaluate the potential efficacy and safety of ribaxamase in a broader patient population by the inclusion of additional IV
beta-lactam antibiotics with ceftriaxone and by enrolling patients with a variety of underlying infections.
Based on our institution's antiobiogram, a previous study showing no benefit in Pseudomonas coverage with use of an antipseudomonal fluoroquinolone and antipseudomonal
beta-lactam, (7) along with our knowledge of mechanisms of resistance, led us to hypothesize that providing "double coverage" for empiric Pseudomonas coverage with floroquinolones in addition to piperacillin-tazobactam would provide no additional coverage.
Ramsey: The switch from second-line options to
beta-lactams saved an estimated $780 per patient and close to $40,000 overall.
MRSA is vulnerable to
beta-lactams when the bacterium's ability to make a building block for its cell wall is disabled.
The best evidence right now is that for simple cellulitis (no purulence, abscess, or exudate), treatment with a
beta-lactam antibiotic is the best option.
The MaxSignal
Beta-Lactam ELISA Test Kit is manufactured to the international quality standard ISO 9001:2008 (ISO CI#: SARA-2009-CA-0114-A).
Continuous infusion of
beta-lactam antibiotics in severe sepsis: A multicenter double-blind, randomized controlled trial.
"We have seen truly impressive bacterial eradication in highly resistant strains generated by combination of this beta-lactamase inhibitor with existing
beta-lactam antibiotics," commented Christopher G.
The Enterome microbiome study, scheduled for completion in the second half of 2014, is expected to provide a better understanding of the harmful effects of
beta-lactam antibiotics on the gut bacterial community.
Empiric combination therapy using a
beta-lactam antibiotic plus an aminoglycoside is no more beneficial than empiric monotherapy using an appropriately broad-spectrum
beta-lactam antibiotic alone for children suspected of having gram-negative bacteremia, according to a report.
The acquisition includes Orchid's
beta-lactam antibiotics manufacturing complex (comprising Cephalosporin, Penicillin and Carbapenem facilities), pharmaceutical research and development facility at Irungattukottai, Chennai and its generic injectable product portfolio and pipeline.