Although earlier studies have shown a relationship between social engagement and cognitive decline, scientists have not fleshed out the relationship between these two factors and levels of
beta-amyloid in the brain.
Both
beta-amyloid and tau clusters are associated with a higher risk of developing dementia, though not everyone with protein tangles goes on to develop symptoms of dementia.
Betaclear will soon be one of the biggest drivers of the country's medical tourism, Santos said, when it becomes the first country to deploy an FDA-approved and commercially available rapid
beta-amyloid detoxification procedure.
While acute sleep deprivation is known to elevate brain
beta-amyloid levels in mice, less is known about the impact of sleep deprivation on
beta-amyloid accumulation in the human brain.
In the new study, researchers at KCL found that when
beta-amyloid destroys a synapse, the nerve cells make more
beta-amyloid -- driving yet more synapses to be destroyed.
They then analysed this data to see if there was a correlation between participants who reported daytime sleepiness or napping and whether they scored positive for
beta-amyloid deposition in their brains.
However, some people have
beta-amyloid plaques, but don't develop
They found
beta-amyloid increases of about 5 percent after losing a night of sleep in brain regions including the thalamus and hippocampus, regions especially vulnerable to damage in the early stages of Alzheimer's disease.
In the study, excessive daytime sleepiness (EDS) was associated with increased accumulation of
beta-amyloid, an important biomarker of AD that manifests in early preclinical stages, wrote first author Diego Z.
'We know that sleep is necessary to clear toxins and
beta-amyloid in the brain,' said study author Prashanthi Vemuri, a research faculty member at the Mayo Clinic, where the study was done.