In this study among 114 patients 44% of the patients had a benign aetiology, 20% had a malignant aetiology and 34% were normal, 8% had
benign lymphadenopathy and another 8% had malignant lymphadenopathy.
The present study consisted of 75 patients, with the highest number of patients 12 (30%) in from the age group of 21-30 years in the cases of
benign lymphadenopathy, in rest of age group incidence remains the same.
The most frequently encountered diagnostic factors among patients with
benign lymphadenopathy were.
Florid follicular hyperplasia, the initial morphology seen in progressive HIV-related benign lymphadenopathy, is characterized by large, irregularly shaped geographic follicles, covering up to two-thirds of the cross-sectional area of the lymph node, surrounded by an attenuated to absent mantle cell zones (Figure 1).
The progressive stages of HIV-related benign lymphadenopathy (FFH [right arrow] MX [right arrow] FI [right arrow] lymphocyte depletion) correlate with the immune status of the patient and parallel the progressive loss of CD4+ T cells, increasing viral load, and collapse of the immune system.
The most common causes of
benign lymphadenopathy are infectious mononucleosis, toxoplasmosis & tuberculosis, may be in the reverse order in the Indian scenario.
871 cases (85.22%) were of
benign lymphadenopathy, of which 357 cases (34.93%) were of reactive nature (including 125 cases with activated histiocytic clusters) and 402 cases (39.33%) were tubercular.
Human herpesvirus-8 DNA sequences in human immunodeficiency virus-negative angioimmunoblastic lymphadenopathy and
benign lymphadenopathy with giant germinal center hyperplasia and increased vascularity.
112 of 186 (63%) patients with
benign lymphadenopathy had a non- specific or reactive etiology.