Among the 19 SH-HCC cases, all showed macrovesicular steatosis, inflammation and
ballooning degeneration, with Mallory hyaline in 16 of 19 cases (84.2%), and pericellular fibrosis in 18 of 19 cases (94.7%).
Signs of the classic HSV cytopathic effect included the presence of intracellular proteinaceous fluid,
ballooning degeneration of epithelial cells, and acantholysis (figure 2, A) as well as intranuclear inclusion bodies and a ground-glass appearance of some nuclei (figure 2, B).
Out of 30 patients only 8 patients had undergone skin biopsy which showed intraepidermal split with
ballooning degeneration of epidermis and lymphocytic inflammatory infiltrates in the dermis.
Schwimmer and his associates, is a steatosis with
ballooning degeneration and/or perisinusoidal fibrosis with or without lobular inflammation and without portal inflammation or fibrosis.
The liver disease in these patients can range from simple NAFLD all the way to nonalcoholic steatohepatitis (NASH), in which histologic findings range from fat plus
ballooning degeneration to fat plus alcoholic hepatitis--like lesions that are impossible to distinguish from those of alcoholic liver disease.