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autoimmune gastritis

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autoimmune gastritis

A rare form of chronic atrophic gastritis, which is most common in African Americans and northern Europeans, characterised by autoimmune destruction of fundic and body glands.

Lab
Serum antiparietal and anti-intrinsic factor antibodies that cause IF deficiency, decreasing available cobalamin, often linked to megaloblastic anaemia
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References in periodicals archive
Cutting edge issues in autoimmune gastritis. Clin Rev Allergy Immunol 2012; 42:269-278.
Autoimmune gastritis diagnosis was established according to the pathological features in biopsy specimens, which was obtained during gastroscopic examination.
Clinical profiles, endoscopic and laboratory features and associated factors in patients with autoimmune gastritis. Digestion 2012; 86: 20-6.
Relationships between autonomic nerve function and gastric emptying in patients with autoimmune gastritis. Clin Auton Res 2016; 26: 189-96.
Autoimmune gastritis in type 1 diabetes: a clinically oriented review.
IFN-a treatment for chronic hepatitis C may appear to be associated with occurrence of autoimmune gastritis, particularly in female patients.
Krishnamurthy and Dayal[2] reported PAT at the GEJ in 3% of adults with BE and Jhala et al[6] reported PAT at the GEJ in oxyntic mucosa of 41% of adults with autoimmune gastritis.
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