Acute
arsenic intoxication: forensic and toxicologic aspects (an observation).
MCHC was significantly decreased in the present study with
arsenic intoxication, which is in agreement with results of Halder et al.
Arsenic intoxication is known to produce symptoms such as dark gray skin color, wart-like keratosis on palms and soles, Mees bands, acne-like skin eruptions, skin cancer, liver and kidney disease, and cerebral changes.
Manifestations of chronic arsenicosis may appear after latent period between six months and 50 years or more.3,4,10 Bowen disease and squamous cell carcinoma may develop under arsenical keratosis.1,2,5 Diagnosis of
arsenic intoxication is often difficult because clinical presentation varies depending on route of exposure, chemical form, dose, and time elapsed since exposure.
Chronic oral
arsenic intoxication as a possible aetiological factor in idiopathic portal hypertension (non-cirrhotic portal fibrosis) in India.
Urine samples are more valid for the diagnosis of
arsenic intoxication, but these too are influenced and often rise dramatically after a seafood meal.
The development of Bowen's disease has been linked to sunlight exposure, human papilloma virus (HPV), and chronic
arsenic intoxication. (7)
Arsenicosis patients in Guizhou show significantly lower MT transcript levels in blood, which may have predisposed this population to
arsenic intoxication.
(9) However, a detailed haematological picture in chronic
arsenic intoxication has hardly been reported in toxicological studies.
(1981) suggested a neurotoxic potential of arsenic after acute
arsenic intoxication of human patients that caused a polyneuropathy with prolonged sensory and motor deficits.
Our group has also reported beneficial effects of vitamins supplementation during
arsenic intoxication (95).