The lining may be eccrine or
apocrine, but as with most sweat gland tumors, the distinction between eccrine and
apocrine differentiation is not clinically important.
While SOX-10 is known to play an important role in melanocyte development and can be used as a diagnostic marker of malignant melanoma, this protein is less studied in tumors of the
apocrine and eccrine sweat glands.
Slanetz, "
Apocrine metaplasia found at MR biopsy: is there something to be learned?," The Breast Journal, vol.
When the body is reacting to an emotion--such as anxiety, stress, or excitement--sweat is released from
apocrine glands.
the whole secretory cell is secreted) whereas sweat glands secrete either
apocrine (secretion occurs via pinchoff of outer cell parts) or eccrine (secretion is released from the cell as a liquid without disintegration).
Hidrocystomas are benign adnexal tumors of eccrine or
apocrine origin.
In some cells the
apocrine blebs are seen protruding into the lumen containing cytoplasmic matrix.
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory disease of the
apocrine sweat glands, characterized by recurrent abscessing inflammation [1].
Hidrocystomas are rare, benign, cystic tumors of sweat glands conventionally classified into
apocrine and eccrine types according to their histological characteristics and presumed histogenetic derivation.
Dermatologic entities with similarities in histologic appearance include hidradenoma,
apocrine cystadenoma, eccrine acrospiroma, papillary eccrine adenoma,
apocrine adenoma, chondroid syringoma, and tubular
apocrine adenoma [2, 4, 7].
Where an
apocrine gland is not formed, there are only two bulges seen.