Noker, "
Antimitotic agents: structure-activity studies with some pyridine derivatives," Journal of Medicinal Chemistry, vol.
Antimitotic agents can cease the mitosis in any phase of the cell cycle.
Synthetic benzophenones, for instance, dihydroxy-4-methoxy benzophenone [2], and 2-aminobenzophenone [3] have turned out to be anticancer and
antimitotic agents, respectively.
Synthesis of a new 4-aza2,3-didehydropodophyllotoxin analogues as potent cytotoxic and
antimitotic agents. Bioorganic and Medicinal Chemistry 19, 2349-2358.
They act as
antimitotic agents in the epidermis by influencing gene transcription resulting in inhibition of the immunological, inflammatory and proliferative processes of the disease [14-16].
An Aden carcinoma is involved in the majority of such cases, but in most cases it is actually the
antimitotic agents that are at fault (mitomycin C, 5-fluorouracil, platinum-based drugs and bleomycin).