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The patient was given two intravitreal anti-VEGF injections for the CNV secondary to angioid streaks. The patient continues to be followed in our clinic and has shown improvement in visual acuity.
The resulting angioid streaks, characterized by irregular red-brown and gray lines extending peripherally from the peripapillary area, are the most common funduscopic finding of PXE.
(1) Angioid streaks and peau d'orange are among the major diagnostic criteria of PXE; comet lesions are one of the minor criteria.
Angioid streaks and comet lesions were present in both of our cases.
PXE should be considered for patients with the fundoscopic finding of angioid streaks. The presence of skin lesions supports this diagnosis.