Medical

amelogenin

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amel·o·gen·in

(am'ě-lō-jen'in)
A class of proteins that form much of the organic matrix during the early development of tooth enamel.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

amelogenin

A structural protein used as a drug to treat PERIODONTITIS. The drug is formulated as a gel that is placed under a flap in the gum surrounding the root of the tooth and promotes regrowth of gum tissue that has been destroyed by the inflammatory process. A brand name is Emdogain.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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References in periodicals archive
In this study we attempt to clarify the distribution of these amelogenin binding partners in the amelogenin mutation mouse, a mouse model of AI.
Reduced hydrolysis of amelogenin may result in X-linked amelogenesis imperfecta.
A PCR-based sex-determination assay in cattle based on the bovine amelogenin locus.
The following data are reported: sex (genetically-assessed by the Amelogenin gene), the consensus 11 -microsatellite genotype (three repetitions), PCR success (%), error rate % (the number of incorrect single-locus genotypes divided by the total number of single-locus genotypes obtained)and the probability of identity associated to each multilocus genotype, calculated for random dyads ([P.sub.id[random]]) and full sibling pairs ([P.sub.id[sibs]]).
Upadhyaye, "Association of amelogenin with high caries experience in indian children," The Journal of clinical pediatric dentistry, vol.
Ooya, "Immunohistochemical detection of amelogenin and cytokeratin 19 in epithelial odontogenic tumors," Oral Diseases, vol.
Occurring within the amelogenin gene, this isn't strictly a classical STR where the size of a repeat element can vary; rather, it turns out that the version of the amelogenin gene carried on the X chromosome (AMELX; twice in females and once in males) is not precisely length-identical with the same region of the amelogenin gene carried on the Y chromosome (AMELY; once in males).
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