Although some studies showed a higher PTTG expression in
acromegalic patients than in NFPA (31, 32), we noted a significantly higher expression of PTTG in NFPA (P=0.04), which was in agreement with the higher rate of invasiveness of this tumor subtype (5, 34, 35).
and other co-workers, (2014) (18,19) showed elevated IGF1 level in
acromegalic patients than normal value before treatment, and after treatment found within the normal range.
Moreover, in another study, decreases in insulin, triglyceride (TG) and fibrinogen levels together with IMT were detected as a consequence of inhibition of GH/IGF-1 secretion in
acromegalic patients (12).
Acromegalic arthropathy: a reversible rheumatic disease.
Antisense Therapeutics, an Australian publicly traded pharmaceutical drug discovery and development company, has enrolled 24
acromegalic patients who have been randomised to one of the two treatment regimens of dosing in the Phase II trial of ATL1103 for the growth disorder, acromegaly, it was reported yesterday.
Byrne, who died in 1783 aged just 22, was huge due to a growth disorder called
acromegalic gigantism where a person produces too much growth hormone.
(9,10) Hypertrophic articular cartilage and the growth of chondrocytes in the articular cartilage may give rise to
acromegalic arthropathy.
Therefore, at the end ofa 12-months phase III study, pasireotide has been approved for Cushing's disease [76], and it is currently in phase III clinical trials for
acromegalic patients and phase II trials for neuroendocrine tumors (NETs).
Using the intubating laryngeal mask airway for ventilation and endotracheal intubation in anesthetized and unparalyzed
acromegalic patients.
Extrahypothalmic growth-hormone-releasing factor (GFR) secretion is a rare cause of acromegaly: plasma GRF levels in 177
acromegalic patients.J Clin Endocrinol Metab 1984; 59:846-9.
To date, only one study, from Argentina, evaluated active
acromegalic patients (n=15) for oxLDL levels and oxidative stress markers in comparison with age- and gender-matched healthy controls (73).