ac·ces·so·ry mol·e·cules

surface receptors on immune cells, which participate in cell-cell interactions and modulate the immunologic outcome. For example, in T-cell recognition of B-cell presented-antigen, the primary interaction occurs through CD3-CD4 binding to MHC and antigen, but this interaction is amplified if concomitant accessory molecule binding also occurs, for example, CD28 to B7.

Farlex Partner Medical Dictionary © Farlex 2012

ac·ces·so·ry mol·e·cules

(ak-ses'ŏr-ē mol'ĕ-kyūlz)

Cell surface adhesion molecules on T cells that are involved in binding of one cell to another cell or in signal transduction.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Mentioned in

CD19

References in periodicals archive

Among the accessory molecules involved in the activation of naive [CD4.sup.+] T lymphocytes, the up-regulation of CD40 is of particular interest in AS because the CD40 pathway is intimately involved in exaggerated inflammation (24).

Adiponectin inhibits oxidization-induced differentiation of T helper cells through inhibiting costimulatory CD40 and CD80

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