A positive culture of the case may suggest
Acanthamoeba infection, but does not confirm
Acanthamoeba infection.
Disseminated
acanthamoeba infection is a rare disease characterized by widespread granulomatous infiltration of the skin and extracerebral organs; it usually occurs in immunocompromised patients.
However, a negative culture does not necessarily rule out
Acanthamoeba infection. Confocal microscopy and polymerase chain reaction assays to detect Acanthamoeba can also assist with diagnosis.
Early diagnosis of
Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.
[26] discussed the relation between
Acanthamoeba infection and S.epidermidis&S.aureus.
To treat the
Acanthamoeba infection, the patient was started on oral itraconazole and intravenous metronidazole; IV pentamidine was added 2 days later.
They conclude that
Acanthamoeba infection rates appear to be closely related to improper maintenance and cleaning of soft lenses by users.
Disseminated
Acanthamoeba infection in a renal transplant recipient.
Evidence of
Acanthamoeba infection was recently found by PCR in brain tissue of a patient with lupus, even without isolating the ameba (8).
In conclusion,
Acanthamoeba infection was demonstrated by hematoxylin and eosin and immunostaining of brain tissue and PCR detection of ameba mitochondrial DNA in brain tissue.
The increasing importance of
Acanthamoeba infections. J Eukaryot Microbiol, 2000; 47: 29-36.
Among their topics are high-throughput screenings: new breeze in anti-Trypanosoma cruzi drug discovery, protein glycosylation in Trypanosoma cruzi and strategies based on mass spectrometry for characterizing glycans and glycoproteins, omics approaches for understanding gene expression in Leishmania: clues for tackling Leishmaniasis, Entamoeba histolytica: from high-throughput technology to new drugs, and gene silencing and therapeutic targets against
Acanthamoeba infections. Distributed in the US by Ingram Content Group.