abdominoperineal resection (APR),

a surgical cancer treatment involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.

Farlex Partner Medical Dictionary © Farlex 2012

abdominoperineal resection

The surgical excision of the lower rectum and anus, resulting in the loss of the anal sphincter and a need for colostomy.

Results
Local control, 60–80%; 60–90% 5-year survival; for larger lesions, RT and 5-FU and mitomycin are used.

APR is less preferred than RT for small lesions + external beam treatment or with radioactive implants—e.g., 198Iridium seeds.

ab·dom·i·no·per·i·ne·al re·sec·tion

(ab-dom'i-nō-per-i-nē'ăl rē-sek'shŭn)

A surgical treatment for cancer involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin, and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Mentioned in

References in periodicals archive

Successful treatment has been reported with methods, such as abdominoperineal resection (APR) and pelvic exenteration, using wide local excision.

Gastrointestinal stromal tumors (GIST) of the anus: A single institution experience

Since being diagnosed she has had chemotherapy, lung surgery, abdominoperineal resection surgery and now has a permanent stoma bag and is on dialysis.

Helped to feel pride

There were 7 (5.9%) patients with wound infections necessitating opening of the port stitches and drainage of superficial infection, bleeding was seen in 5(4.2%) requiring conversion to open, three patients (2.5%) developed intra abdominal abscess following anterior resection, abdominoperineal resection (APR) and transabdominal preperitoneal (TAPP) inguinal hernia requiring percutaneous drainage under ultrasound guidance.

Feasibility of robotic surgery in a developing country, a public sector perspective

Patients with adenocarcinoma of the rectum within 5 cm from the anal verge underwent abdominoperineal resection and those with tumor above 5 cms.

LAPAROSCOPIC ASSISTED SURGERY IN COLORECTAL CANCER: OUR EXPERIENCE

Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer.

Preliminary Outcome of Individualized Abdominoperineal Excision for Locally Advanced Low Rectal Cancer

The exception to this is perhaps with sigmoidorectal intussusception in which initial reduction may avert an abdominoperineal resection and a permanent colostomy, but this remains contentious.

Kaposi sarcoma: an unusual cause of intussusception in an adult patient

The abdominoperineal resection was performed (Figure 1).

Huge Anorectal Malignant Melanoma and Treatment/Buyuk Anorektal Malign Melanom ve Tedavisi

After about one month, the patient underwent abdominoperineal resection of the rectum, which relieved his anal pain, but subsequently he developed perineal pain and dysuria.

Successful opioid dose reduction after ganglion impar block in a patient with postoperative micturition pain

However, in cases in which a tumor-free distal resection margin is not achievable, a locally far-advanced tumor is present, and the patient shows severely decreased anal function preoperatively, surgeons should perform abdominoperineal resection (APR) requiring a permanent colostomy.

Comparison of Anthropometric Parameters after Ultralow Anterior Resection and Abdominoperineal Resection in Very Low-Lying Rectal Cancers

In the robotic-assisted surgery group, nine patients underwent anterior resection (42.9%), seven underwent low anterior resection (33.3%), four underwent ultra-low anterior resection (19%), and only one patient (4.8%) underwent abdominoperineal resection (APR).

Robotic-Assisted versus Conventional Laparoscopic Approach for Rectal Cancer Surgery, First Egyptian Academic Center Experience, RCT

Abdominoperineal resection (APR) is one of the techniques performed in the surgical treatment of the distal rectal cancer [1].

Transvaginal Small Bowel Evisceration following Abdominoperineal Resection

Additionally, this modality allows the surgeons to perform sphincter saving procedure instead of abdominoperineal resection and permanent ileostomy construction.

Effect of human amniotic membrane on prevention of colorectal anastomosis leakage in cases with neoadjuvant radiotherapy: an experimental animal study