The response to spatial memory and motor activity was tested in a
Y-maze procedure.
Thus, our 'bee school' within the
Y-maze allowed the bees to learn how to use arithmetic operators to add or subtract.
Caption: Figure 5: Graphic representation of the working memory (a) and spatial reference memory (b) errors as well as the time past in radial maze (c) before and after scopolamine exposition in rats treated with different substances into the
Y-maze. SHAM 1 = sham-operated rats treated with vehicle as normal control 1; SHAM 2 = sham-operated rats treated with vehicle as normal control 2; OVX = ovariectomized rats treated with vehicle as negative control; PIR = ovariectomized rats treated with piracetam at the dose of 1.5 mg/kg BW as positive control 1; E2V = ovariectomized rats treated with estradiol valerate at the dose of dose 1 mg/kg BW as positive control 2; FU 50 and 200 = ovariectomized rats treated with F.
It is also possible that AIP in the optic tectum is unresponsive to the
Y-maze stimulus, but alternate environmental stimuli, such as altered light exposure, may induce AIP up-regulation in this brain region.
In order to determine the period of drug treatment after OVX surgery, we evaluated the effect of ovariectomy on learning and memory activities in different periods (4 and 8 weeks) after surgery using
Y-maze test at first, in preliminary experiments.
In this study, the mice were assigned to independent groups (5 in each group), except in the
Y-maze test where there were 6 animals per group.
A significant decrease in the passive avoidance learning and spatial
Y-maze alternation scores was observed in the A[beta] group, in comparison with the A[beta] + CA group.
Exercise improves memory acquisition and retrieval in the
Y-maze task: relationship with hippocampal neurogenesis.