Medical

Tudor Domain

A 50-amino acid structural motif that is present in the human tumour suppressor p53-binding protein, AKAP1 (A-kinase anchor protein) and ARID4A (AT rich interactive domain 4A) and is involved in RNA binding.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive
Among RNA-processing proteins, tudor domain containing (TDRD) family proteins are important for germ-cell specific small RNA, piRNA biogenesis (Bak et al., 2011).
TDRD9 contains an ATPase/DExH-box ATPase (DExH)type helicase and a Tudor domain and functions in silencing LINE-1 retrotransposon during spermatogenesis.
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi.
Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.
Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.