[1] The pathognomonic feature of acute hypocalcaemia is tetany (typified by a
Trousseau's sign) and is usually preceded by paraesthesia (peri-oral and acral), increased neuromuscular irritability (Chvostek's sign) and muscle cramps.
Physical examination of someone with hypocalcemia may show tetany, but it is also possible to provoke tetany of the facial muscles by tapping on the facial nerve (a phenomenon known as Chvostek's sign) or by using the cuff of a sphygmomanometer to temporarily obstruct the blood flow to the arm (a phenomenon known as
Trousseau's sign in latent tetany).
The physical examination of the patient, who had lost more than 10% of her body weight (6 kg) in one month, revealed a positive Chvostek's sign and a negative
Trousseau's sign. The results of the laboratory examination were as follows: serum calcium 6.8 mg/dL (8.2-10.5 mg/dL); phosphorus 4 mg/dL (2.5-4.8 mg/dL); albumin 3.6 g/dL (3.5-5.2 g/dL); parathormone (PTH) 144.7 pg/mL (15-65 pg/mL); 25-hydroxy vitamin D 25(OH)D 9 ng/mL (<10 ng/ml indicates severe deficiency); potassium 3.5 mEq/L (3.5-5.5 mEq/L); hemoglobin 11.8 g/dL; hematocrit 37.5%; ferritin 20.92 ng/mL (5-148 ng/mL); and vitamin B12 193 pg/mL (193-982 pg/mL).