Serum hepcidin and soluble
transferrin receptor in the assessment of iron metabolism in children on a vegetarian diet.
Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Akkermans et al., "The value of soluble
transferrin receptor and hepcidin in the assessment of iron status in children with cystic fibrosis," Journal of Cystic Fibrosis, vol.
Beguin, "Soluble
transferrin receptor for the evaluation of erythropoiesis and iron status," Clinica Chimica Acta, vol.
(20.) Erhardt JG, Estes JE, Pfeiffer CM, Biesalski HK and NE Craft Combined measurement of ferritin, soluble
transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique.
It is reported that insulin increases externalisation of the
transferrin receptor, thereby stimulating cellular iron uptake.
(4) More specialized tests to differentiate IDA from anemia of chronic disease (ACD) include hepcidin and
transferrin receptor levels.
Soluble
transferrin receptor was decreased to 1.3mg/L (N: 2.2-5).
Serum protoporphyrin levels, plasma hepcidin and
transferrin receptor saturation assay14 are alternative tests.
Keywords: 17-[beta]-estradiol; Hepcidin; Intracellular labile iron; Ferroportin;
Transferrin receptor; MCF-7; SKOV-3
Transferrin is can bind two [Fe.sup.3+] ions with very high affinity and donate iron to cells throughout the body via
transferrin receptor 1 (TfR1) (Kovac et al., 2009).