Theobald Smith phenomenon
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The·o·bald Smith phe·nom·e·non
(thē'ō-bahld smith), a phenomenon observed in guinea pigs that had survived use for diphtheria antitoxin standardization, the animals having been rendered highly susceptible to subsequent inoculation of horse serum.
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Smith,
Theobald, U.S. pathologist, 1859-1934. Theobald Smith phenomenon - guinea pigs that had survived use for diphtheria antitoxin standardization were highly susceptible to subsequent inoculation of horse serum.
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