Moreover, deterioration of the microcirculation due to oxidative stress occurs in the
splanchnic region during LC insufflation.
Concurrent chronic liver disease (CLD), inherited thrombophilic disorders, and occult malignancies for which
splanchnic thrombosis was the presenting symptom were also evaluated and recorded.
In conclusion, the negative inotropic effect of NSBB seems to be counterbalanced by a smaller decrease ofvascular resistances after LVP, probably due to
splanchnic ^2-blockade.
Another multicenter, retrospective European study with 94 patients from 17 centers looked at NOAC use for
splanchnic vein thrombosis, cardiac arrhythmias, peripheral deep vein thrombosis (DVT), and PE [19].
Conceivably, the repeated episodes of crampy abdominal pain throughout the hospitalization were caused by transient
splanchnic arterial vasospasm, eventually leading to bowel necrosis and death.
Management options in chylous ascites include discontinuing offending medications (CCBs), altering the diet to predominantly medium chain triglycerides (MCT), somatostatin analogues (they increase
splanchnic arteriolar resistance and decrease lymph flow) [11], and instituting total parenteral nutrition (TPN).
Excess use of meth has been implicated in the formation of renal and
splanchnic artery aneurysms [2] and may cause myocardial infarction or stroke [3, 4].
Studies have stated that venous thrombosis following pancreatitis is frequent and typically manifests as
splanchnic vein thrombosis (SVT), predominantly involving splenic vein (SpIV) [7].
Distal lesions are more often associated with renal and/or
splanchnic arterial disease, which is consistent with the case presented here as the infraceliac aorta was of normal caliber and there was no associated narrowing in the renal or
splanchnic vasculature.
Autopsy findings typically include hemorrhage and microthromboses in the
splanchnic organs, (i.e., intestine, liver, lungs, kidneys, pancreas, and spleen), heart, brain, cornea, and skin [43, 49-51].