Medical

sex hormone-binding globulin

Also found in: Acronyms, Wikipedia.
(redirected from Sex hormone binding globulin)

sex hor·mone-bind·ing glob·u·lin (SHBG),

a plasma β-globulin, produced by the liver, which binds testosterone and, with a weaker affinity, estrogen; serum levels of SHBG in women are twice those found in men; serum concentrations are increased in certain types of liver disease and in hyperthyroidism but are decreased with advancing age, by androgens, and in hypothyroidism.
Synonym(s): testosterone-estrogen-binding globulin
Farlex Partner Medical Dictionary © Farlex 2012

sex hor·mone-bind·ing glob·u·lin

(SHBG) (seks hōrmōn-bīnding globyū-lin)
Plasma β-globulin, produced by the liver, which binds testosterone and, with a weaker affinity, estrogen; serum levels of SHBG in women are twice those found in men.
Synonym(s): testosterone-estrogen-binding globulin.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Mentioned in
References in periodicals archive
FastPack IP SHBG provides rapid, fully-quantitative and highly accurate Sex Hormone Binding Globulin results to clinicians and patients," stated Dr Wajdi Abdul-Ahad, the company's VP of Assay Development, whose team developed this assay.
Qualigen wins US FDA's clearance for its FastPack IP SHBG Assay
Investigations on testosterone and sex hormone binding globulin levels were carried out using enzyme-linked immunosorbent assay and concentrations of testosterone and SHBG was interpolated by Spline and Lowess method using the Spline Curve via graph prism version 6.5.
Epidemiological Assessment of Testosterone Levels in Women Population: A Factorial Analysis of Cell Proliferation
Gersak, "Association between serum levels and pentanucleotide polymorphism in the sex hormone binding globulin gene and cardiovascular risk factors in females with polycystic ovary syndrome," Molecular Medicine Reports, vol.
Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Dunn, "Association of decreased sex hormone binding globulin and cardiovascular risk factors," Arteriosclerosis, Thrombosis, and Vascular Biology, vol.
Low Levels of Sex Hormone-Binding Globulin Constitute an Independent Risk Factor for Arterial Stiffness in Korean Women
Keywords: Homeostatic model assessment-Insulin resistance, Insulin resistance, Sex hormone binding globulin, Type 2 diabetes mellitus.
ASSOCIATION OF SERUM SEX HORMONE BINDING GLOBULIN WITH TYPE 2 DIABETES MELLITUS
Abnormal puberty in paediatric Cushing's disease: relationship with adrenal androgen, sex hormone binding globulin and gonadotrophin concentrations.
Sex Hormone-Binding Globulin in Children and Adolescents
Serum testosterone and SHBG levels of metabolic syndrome and healthy control grup Healthy Metabolic P control syndrome (n=30) (n=30) median IQR median IQR Total 589 520.5-687.5 460 371.5-567 0.004 testosterone 25 Bioavailable 198.5 129.25-224 173 135.25-201 0.29 testosterone SHBG 65.5 52.28-90.15 49.5 38.65-62.33 0 003 Calculated 8.68 6.28-10.02 7.29 6.02-8.93 0.25 free testosterone IQR: Interquartile range, SHBG= Sex hormone binding globulin Table 3.
Late-onset hypogonadism in male patients over 60 years of age with metabolic syndrome / Altmis Yas Ustu Metabolik Sendromlu Erkek Hastalarda Gec-Baslayan Hipogonadizm
The authors only reported an inverse association between serum sex hormone binding globulin (SHBG) concentration and prostate cancer risk.
Serum testosterone levels, testis volume, and the risk of prostate cancer: are these factors related? Serum testosteron duzeyi, testis hacmi, ve prostat kanser riski: aralarinda basit bir iliski var mi?
The remaining is (1) bound to albumin, a carrier protein in the blood plasma (yet still bioavailable), or (2) complexed with sex hormone binding globulin (SHBG) and no longer bioavailable.
The "masculine hormone"--and SCI (part 1)
Sex hormone binding globulin: origin, function and clinical significance.
Do you know your sex hormone status?
GTx also said the drug increased levels of sex hormone binding globulin, a protein that binds to testosterone, thus reducing levels of free testosterone--the form of the hormone prostate cancer cells use for growth.
Higher doses of an experimental prostate cancer drug being developed by GTx Inc (Los Angeles CA) were shown in a trial to lower testosterone levels, the male hormone the cancer cells need to grow and spread
Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts.
A practical guide to diagnosis, management and treatment of testosterone deficiency for Canadian physicians
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.