SHROOM3

A gene on chromosome 4q21.1 that encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins, which may be involved in regulating cell shape. A homologue in mice is required for proper neurulation.

References in periodicals archive

Many loci have been identified, including FTO (Hubacek et al., 2012); ACTN4, TRPC6, INF2, UMOD, MHC, PLA2R1/sPLA2, complement factors, APOL1 (Friedman & Pollak, 2011); and GATM/SPATA5L1 and SHROOM3 (Li, 2015).

Applying the Public Health Exposome Model to Improve Kidney Disease Outcomes for Patients and Populations

These imply future studies in relation to the analysis of apoptosis pathways in mesenchymal stem cells [41] and regulation of genes that have been related to NTD as SHROOM3 and can be sensitive to the action of glycoalkaloids during critic periods of embryogenesis [48, 49] and the study of structural changes of the cytoskeleton induced by different concentrations of [alpha]-solanine [50].

A Reliable and Reproducible Model for Assessing the Effect of Different Concentrations of [alpha]-Solanine on Rat Bone Marrow Mesenchymal Stem Cells

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