Faure et al., "Null mutations causing depletion of the type 1
ryanodine receptor (RYR1) are commonly associated with recessive structural congenital myopathies with cores," Human Mutation, vol.
Bidasee, "Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac
ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum [Ca.sup.2+]-ATPase (SERCA2) in diabetes," Molecular and Cellular Biochemistry, vol.
Shibata, "Mutant mice lacking
ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium/calmodulin-dependent protein kinase II in the hippocampus," Brain Research.
Insecticidal anthranilic diamides: a new class of potent
ryanodine receptor activators.
Santoro et al., "Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac
ryanodine receptor," Circulation Research, vol.
FKBP12.6-mediated stabilization of calcium-release channel (
ryanodine receptor) as a novel therapeutic strategy against heart failure.
New and selective
ryanodine receptor activators for insect control.
Okabe, "Superoxide anion radical-triggered Ca2+ release from cardiac sarcoplasmic reticulum through
ryanodine receptor Ca2+ channel," Molecular Pharmacology, vol.
The first evidence of S-nitrosation involvement in this class of pathologies involves the S-nitrosation, and the subsequent hyperactivation, of the [Ca.sup.2+] release channel
ryanodine receptor 1 (RyR1).
In sections on herbicides, fungicides, and insecticides, they examine such classes as triazine herbicides, imidazolinone herbicides, morpholine fungicides for treating powdery mildew, avermectin insecticides and acaricides, phenylpyrazole-containing fiprole insecticides, and pyrazolylpyridine activators of the insect
ryanodine receptor.
Mainly, neurotoxins bind to surface membrane receptors (sites), but many peptides penetrate the cell membrane and activate components at its cytosolic interface; for example, maurocalcine and imperatoxin A penetrate the membrane bilayers and activate the intracellular
ryanodine receptor to provoke the intracellular sequestrated calcium release [31-35].