CREBBP

A gene on chromosome 16p13.3 that encodes a ubiquitously expressed protein involved in the transcriptional coactivation of various transcription factors. CREBBP acts as a scaffold to stabilise additional protein interactions with the transcription complex; it has intrinsic histone acetyltransferase activity, and acetylates both histone and non-histone proteins.

Molecular pathology
CREBBP mutations cause Rubinstein-Taybi syndrome (RTS); chromosomal translocations of CREBBP are associated with acute myeloid leukaemia.

RTS

Abbreviation for radial tunnel syndrome.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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References in periodicals archive

The Moscow Interbank Currency Exchange (MICEX) intends to shed its interest in the Depository Clearing Company (DCC) to stock market operator Russian Trading System Stock Exchange (RTB:RTSX) by 1 March, vice-president Vladimir Gusakov told reporters on Friday.

MICEX to offload DCC stake to RTS by 1 March

The community, made up of 15,400 member locations around the world, will be given direct market access to the Moscow Interbank Currency Exchange (MICEX) and the Russian Trading Systems (RTS).

-BT Radianz Cloud to get access to ING services

The Russian government's plans to transform Moscow into a financial hub have taken a step forward after the countries main stock and derivatives exchanges MICEX and Russian Trading Systems (RTS) agreed a non-binding deal to merge.

Moscow financial hub draws closer with RTS/MICEX merger

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