A diagnosis of atypical pseudocholinesterase or pseudocholinesterase deficiency was suspected at this time.
(2) If any of these milder variants are combined with an acquired quantitative pseudocholinesterase deficiency such as has been shown in pregnancy, an additive effect resulting in a significantly prolonged response to succinylcholine would be expected.
Rocuronium antagonized by sugammadex for series of electroconvulsive therapy in a patient with
pseudocholinesterase deficiency. J ECT 2011; 27:e47-e48.
Complete
pseudocholinesterase deficiency: genetic and immunologic characterization.
Use with caution in patients with severe hepatic disease,
pseudocholinesterase deficiency, or a history of sensitivity to amide-type anesthetics.
A 17-year-old girl with a history of von Willebrand' s disease and
pseudocholinesterase deficiency was referred to our department with a 1-year history of a progressively enlarging tongue mass.
Batistaki et al recently reported a patient with another contraindication to succinylcholine, pseudocholinesterase deficiency, where rocuronium (0.4 mg/kg) and sugammadex (2 mg/kg) were used to avoid prolonged apnoea during this patient's ECT (4).
Rocuronium antagonized by sugammadex for series of electroconvulsive therapy (ECT) in a patient with pseudocholinesterase deficiency. J ECT 2011; 27:e47-48.