Medical

protein chip

Also found in: Dictionary, Encyclopedia, Wikipedia.
(redirected from Protein microarray)

protein chip

an orderly arrangement of proteins, immobilized as spots on a matrix at precise locations, to form an array, analogous to DNA CHIP/MICROARRAY. Protein chips can be fabricated by robotically depositing proteins/antibodies on to the surface of a microscope slide. A labelled (see LABEL protein sample, which may contain many analyte proteins, can be applied to the chip. After incubation sample proteins that bind to their capture proteins on the chip can be detected and identified by locating the position/intensity of the label, for example fluorescence. A protein chip allows thousands of proteins to be studied simultaneously. It can be used, for example, for profiling proteins in cells under different conditions and for studying protein-protein and protein-small molecule interactions (see PROTEOMICS).
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
Mentioned in
References in periodicals archive
To validate altered glycopatterns of urinary protein between DN and NDRD, urinary proteins from another 32 patients (15 with DN, 17 with NDRD) were collected to prepare the urinary protein microarray. The clinical information of patients is shown in [Supplementary Table 1] [SUPPORTING:1].
Baiker et al., "Systematic analysis of the IgG antibody immune response against varicella zoster virus (VZV) using a self-assembled protein microarray," Molecular BioSystems, vol.
In present study, we found that the glycopatterns of Sia[alpha]2-6Gal/GalNAc showed increased tendency with development of DN, and urinary protein microarray also confirmed this result.
A lateral flow protein microarray for rapid and sensitive antibody assays.
A direct comparison of ELISA and protein microarray was performed on 30 human sera as an integral part of the comprehensive validation of the microarray technique.
Defining the humoral immune response to infectious agents using high-density protein microarrays. Future Microbiol.
Protein microarray is a technique used in most biomedical applications for determining the presence and quantity of proteins in a biological system.
A confirmatory assay based on a protein microarray was performed as described (10,21) by using the spike S1 subunits of MERS-CoV, human CoV-OC43, and SARS CoV.
Protein Microarrays. Protein microarray is a more recent technology, providing a platform for high-throughput proteomics.
Dr Alyssa Barry from the Walter and Eliza Hall Institute's Infection and Immunity division is using 'protein microarray' technology to screen human blood serum samples for immunity to proteins produced by the malaria-causing Plasmodium falciparum parasite.
Microzyme[R] Colorimetric protein microarray system for the determination of various autoantibodies including Sm, RNR SSA-60, Ro-52, SSB, Scl-70, Jo-1, CENP-B, dsDNA, and Ribosomal R
3:45pm-4:30pm Advances in Protein Microarray Technology for
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.