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Postexposure prophylaxis

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Postexposure prophylaxis (PEP)

Any treatment given after exposure to a disease to try to prevent the disease from occurring. In the case of rabies, PEP involves a series of vaccines given to an individual who has been bitten by an unknown animal or one that is potentially infected with the rabies virus.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
M2 PHARMA-February 12, 2018-FDA Approves Grifols Higher Potency Rabies Post-Exposure Prophylaxis Medication
Additional studies have demonstrated that Elpida has a prolonged blood plasma half-life suitable for both a once weekly formulation and a new long-acting injectable formulation that is effective for at least 30 days of treatment and pre- and post-exposure prophylaxis.
A self-administered structured questionnaire consisting of questions regarding incidence of NSSIs that occurred during the past 3 months, circumstances of the injury, what was done after the exposure, notification to concerned authority, lab investigations, and post-exposure prophylaxis was used to collect the relevant information from the participants.
Three letters are published in relation to an Editorial by Smith and Aerts in March last year, debating the merits of post-exposure prophylaxis in contacts of new cases.
(1.) Antiretroviral Therapy Guidelines for HIV-infected Adults and Adolescents including Post-exposure Prophylaxis. New Delhi: NACO, Ministry of Health and Family Welfare, Government of India; 2008.
Other initiatives include getting pre-exposure rabies vaccination (recommended if one is traveling or living in a location where exposure to rabid and potentially rabid animals is likely), the treatment of bite victims through post-exposure prophylaxis (PEP).
Objective: To evaluate public knowledge regarding predisposing factors, fatality and prevention of Tetanus and Rabies and attitudes toward vaccination and post-exposure prophylaxis.
In terms of post-exposure prophylaxis, unprotected anal intercourse is a low-risk activity for HIV transmission, and it is appropriate to use 2-drug PEP.
Occupational exposure to HIV and the use of post-exposure prophylaxis. Occup.Med:2000:50(6): 387-391.
Almost 90% arrived too late for HIV post-exposure prophylaxis. The delay was often due to the child's difficulty in disclosing abuse to older female relatives, or because adolescent girls did not want to admit to relatives that they were sexually active.
In early 2008, Novartis announced that it would supply RabAvert for post-exposure prophylaxis (PEP) use only.
Additional information and guidance regarding management of specific exposures are available from the National Clinicians' Post-Exposure Prophylaxis Hotline by telephone (888-448-4911) or online (http://www.ucsf.edu/hivcntr).
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