Endometrial samples were obtained by dilatation and curettage or
pipelle biopsy.
Endometrial sampling was performed using a
Pipelle device, and dilatation and curettage was required for two patients due to cervical stenosis.
Samples were collected by way of various methods, including Pap smear, endocervical brushings and curettage, and endometrial
pipelle. The pathologic findings in endocervical samples coincided with the final surgical pathology in 9 of 10 patients with benign findings, 1 of 6 patients with dysplasia, and 2 of 2 patients with cancer.
Further, a prehysterectomy study by Rodriguez et al demonstrated that
Pipelle endometrial biopsy sampled an average of only 4% (range, 0%-12%) of the endometrial surface area.
Methods: This double-blind, placebo-controlled trial was conducted at Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey, from May to November 2015, and comprised patients undergoing endometrial biopsy with
Pipelle. Intrauterine lidocaine infusion, paracervical block with lidocaine, intravenous tenoxicam or 4ml intravenous normal saline administered prior to biopsy.
Comparison of the histopathological diagnoses of preoperative dilatation and curettage and
Pipelle biopsy.
NPs are able to make a diagnosis, recommend and prescribe treatment and carry out procedures such as
pipelle (endometrial) biopsy and Mirena insertion, if that is the treatment option the woman chooses.
Infertile patients with good response to controlled ovarian hyper-stimulation (COH) but with one or two unsuccessful IVF/ET attempts were treated at least 4 times by endometrial biopsy using a biopsy catheter (
pipelle device) during the menstrual cycle, before the next IVF-ET cycle.
Type of specimen Cases Percentage Endometrial curretings 18 34.6 TAH and BSO 15 28.8 tah 04 7.6
Pipelle 07 13.4 TABLE 4: Age range of patients with endometrial carcinomas.