parasympatholytic

[par″ah-sim″pah-tho-lit´ik]

1. producing effects resembling those of interruption of the parasympathetic nerve supply of a part; having a destructive effect on the parasympathetic nerve fibers or blocking the transmission of impulses by them.

2. anticholinergic (def. 2).

par·a·sym·pa·tho·lyt·ic

(par'ă-sim'pă-thō-lit'ik),

Relating to an agent that annuls or antagonizes the effects of the parasympathetic nervous system; for example, atropine.

Farlex Partner Medical Dictionary © Farlex 2012

anticholinergic

adjective Referring to an agent or effect that suppresses or inhibits acetylcholine activity.

noun Any agent that inhibits parasympathetic activity by blocking the neurotransmitter acetylcholine; anticholinergics are used for asthma, COPD, diarrhoea, nausea, vomiting, Parkinson’s disease and to decrease smooth muscle spasms (e.g., in the urinary bladder); anticholinergics may be antimuscarinic, ganglionic blockers and neuromuscular blockers.

par·a·sym·path·o·lyt·ic

(par'ă-sim'pă-thō-lit'ik)

Relating to an agent that annuls or antagonizes the effects of the parasympathetic nervous system (e.g., atropine).

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

parasympatholytic

Pertains to a drug that blocks the effects of the parasympathetic nervous system. Examples: atropine, cyclopentolate. Syn. antimuscarinic, anticholinergic, atropine-like. See acetylcholine; cycloplegia; mydriatic.

par·a·sym·path·o·lyt·ic

(par'ă-sim'pă-thō-lit'ik)

Relating to agent that annuls or antagonizes effects of parasympathetic nervous system; e.g., atropine.

Medical Dictionary for the Dental Professions © Farlex 2012

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References in periodicals archive

Atropine is a parasympatholytic alkaloid used as an antidote to Ache inhibitors (5,6); it acts through competitive occupation of nicotinic and muscarinic cholinergic receptors (8).

A Rat Mammary Tumor Model Induced by the Organophosphorous Pesticides Parathion and Malathion, Possibly through Acetylcholinesterase Inhibition

Atropine and other anticholinergic drugs are parasympatholytic because of their marked affinity for acetylcholine receptor sites on postganglionic parasympathetic nerves, where they act as acetylcholine blockers.

Metered dose inhaler therapy for asthma, bronchitis, and emphysema

These results indicate that in male and female cases the parasympathetic reactivity is decreased though, this parasympatholytic effect is seen more in the female cases than the male cases as supported by other workers.

Evaluation of cardiovascular autonomic control in chronic pain patients using isometric handgrip and deep breath maneuvers

Patients with cardiac, hepatic, renal disease, leprosy, hypertension, diabetes mellitus and those on sympathomimetic, parasympatholytic, antihypertensive drugs and also patients below the age of 13 year were excluded from the study.

A study of autonomic function tests in patients with chronic severe anemia

Abstract: The avian iris is mainly composed of striated muscle fibers, and the topical parasympatholytic drugs used in mammals to induce pupil dilation are ineffective in birds.

Safety and efficacy of bilateral topical application of rocuronium bromide for mydriasis in European kestrels (Falco tinnunculus)