hand-foot syndrome

hand-foot syndrome

a painful desquamative syndrome associated with 5-fluorouracil, especially if given in a continuous administration and with cytarabine.

Farlex Partner Medical Dictionary © Farlex 2012

hand-foot syndrome

Sickle cell dactylitis Hematology A 'crisis' in sickle cell anemia caused by sludging of RBCs in vessels and characterized by symmetric infarction of the small bones of the hand and foot, periosteal neoosteogenesis, pain and swelling that may occur as early as age 18 months, often resolving spontaneously within 1-4 wks. See Sickle cell anemia.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.