Most of the dogs were presented with initial signs of nyctalopia, followed by progressive hemerlopia until the affected animal was totally blind.
All 31 affected dogs described in present report showed no obvious visual impairment except nyctalopia at initial stage which gradually progress to day blindness in few months to years resulting in complete blindness.
Vitamin A deficiency is a global issue and can result a number of health issues, including reversible night blindness, or
nyctalopia. Young children and pregnant women are most at risk; according to the World Health Organization (WHO), as many as 250 million school age children may be affected.
Nyctalopia had begun in early childhood with onset ranging from 2 to 6 years of age.
Wagner syndrome may further be differentiated from Snowflake degeneration by its alternative genetic mutation (in CSPG2), more pronounced chorioretinal atrophy,
nyctalopia, pseudoexotropia from the congenital temporal displacement of the fovea, and poorer end visual outcome.
A patient presents with a loss of peripheral vision and
nyctalopia.
Despite performing better on the acuity chart, she had continuous episodes of poor night vision (
nyctalopia), frosty blurring of vision (described as 'looking through glass' or 'through water') or a 'bush fire' effect and 'shimmering vision'; this is typically reported by patients as the 'ceiling fan effect' (when closing both eyes one is left with an image of multiple ceiling fans whirring around).
c)
Nyctalopia is thought to more common than oscillopsia in BCR
Patients with RP may complain of difficulties with their vision in dimly lit surroundings or total
nyctalopia. On examination, typical findings are a constricted visual field, retinal bone-spicule pigmentation, arteriolar attenuation and waxy optic disc pallor.