A combined diet and exercise program resulted in a 45% increased likelihood that obese psoriasis patients would achieve a PASI 50 response at week 16, with a
number needed to treat of 7.
Though only a minority of children in the study had a peaked tympanogram, failure rates for these were low in both treatment and placebo groups, and the
number needed to treat to prevent treatment failure was 1 in 29.
Terms such as relative risk, absolute risk, p values, confidence intervals,
number needed to treat (NNT), number needed to harm (NNH), likelihood ratios, statistical significance, or clinical significance are poorly understood by most physicians.
Number needed to treat (NNT) to benefit one patient at any selected endpoint
6.3%; hazard ratio 0.62, 95% CI 0.56-0.69;
number needed to treat 42).
At this early stage of its development, a good way to assess Vilazodrone's relative effectiveness is by calculating the "
number needed to treat" (NNT).
In the Multiple Outcomes of Raloxifene Evaluation, or MORE trial, which evaluated women who had osteoporosis rather than a high risk of invasive breast cancer, the absolute risk reduction for invasive breast cancer was 3.1 fewer cases for every 1,000 woman-years of raloxifene use) The
number needed to treat (NNT) to prevent one case of cancer: 323 women for i year.
They found the
number needed to treat, known as NNT, was 20 patients.
Estimates of the
number needed to treat to prevent one case of pre-term birth are as low as one in six.
Number needed to treat (NNT) is a measure of clinical effect that has been called medicine's "secret stat" (Box 1, page 78).
This translates into a
number needed to treat of three, meaning at 6 weeks every third patient will benefit from receiving PT as opposed to WS.
Trial evidence would suggest that its benefit is limited to reduction of awareness in high-risk individuals if one is prepared to accept a very large
number needed to treat in that regard.