Medical

myelin-associated glycoprotein

Also found in: Acronyms, Wikipedia.

myelin-associated glycoprotein

A glycoprotein in myelin of central and peripheral nervous systems. Anti-MAG antibodies are detected in 50% of patients with IgM paraproteinemia and peripheral neuropathy, and may occur in some patients with multiple sclerosis, Guillain-Barré syndrome, chronic polyneuropathy or myasthenia gravis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Mentioned in
References in periodicals archive
Quarles, "The myelin-associated glycoprotein is enriched in multivesicular bodies and periaxonal membranes of actively myelinating oligodendrocytes," The Journal of Cell Biology, vol.
Trapp, "Myelin-associated glycoprotein. Location and potential functions," Annals of the New York Academy of Sciences, vol.
Seilheimer et al., "Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function," Neuron, vol.
The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury
Popko, "Demyelination and altered expression of myelin-associated glycoprotein isoforms in the central nervous system of galactolipid-deficient mice," Journal of Neuroscience Research, vol.
Fallis et al., "Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosis," Journal of Neuroimmunology, vol.
Autoimmune T-cell reactivity to myelin proteolipids and glycolipids in multiple sclerosis
Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain.
Calpain Inhibitor Reduces Cancer-induced Bone Pain Possibly Through Inhibition of Osteoclastogenesis in Rat Cancer-induced Bone Pain Model
(1994) A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration.
MAP kinase cascades regulating axon regeneration in C. elegans
(1995) Multiple myelinated axons in the optic nerve of mice deficient for the myelin-associated glycoprotein. Glia 14 (2), 115-122.
Abbreviations: CG: 1-O-cholesteryl-[beta]-D-glucopyranoside; DIM: detergent-insoluble membrane; GlcCer: glucosylceramide; GlcT-1/GCS/UGCG: glucosylceramide synthase (ceramide glucosyltransferase); GSLs: glycosphingolipids; MAG: myelin-associated glycoprotein; Phgdh: phosphoglycerate dehydrogenase; PSAT: 3phosphohydroxypyruvate aminotransferase; PSP: 3-phosphoserine phosphatase; PtdGlc: phosphatidylglucoside; SPT: serine palmitoyltransferase.
A world of sphingolipids and glycolipids in the brain--novel functions of simple lipids modified with glucose
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.