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micrococcal endonuclease

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mi·cro·coc·cal en·do·nu·cle·ase

an enzyme, produced by a member of the genus Micrococcus, which cleaves nucleic acids to oligonucleotides terminating in 3'-phosphates.
Synonym(s): micrococcal nuclease, spleen endonuclease, spleen phosphodiesterases
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References in periodicals archive
The use of micrococcal nuclease digestion in DNA fragmentation may be more biologically relevant than ultrasonic shearing because plasma DNA exhibits nonrandom fragmentation patterns related to the positioning of nucleosomes (7, 8).
Quality Materials for Quality Assurance in the Analysis of Liquid Biopsy Samples
NETs treated with micrococcal nuclease (MNase) showed specific DNA bands of under 100 bp in size (Figure 1(b), left panel).
Neutrophil Extracellular DNA Traps Induce Autoantigen Production by Airway Epithelial Cells
A micrococcal nuclease homologue in RNAi effector complexes.
Tudor domain containing protein TDRD12 expresses at the acrosome of spermatids in mouse testis
Briefly, extracted DNA was hydrolyzed with micrococcal nuclease, spleen phosphodiesterase, and nuclease P1.
The effect of morphine on mitomycin C-induced DNA damage and repair
In the second stage this immune-selected chromatin bound to agarose is subjected to non-specific fragmentation either using sonication or mild micrococcal nuclease digestion.
Localization of hyperacetylated histone H4 on the SV40 genome during the SV40 life-cycle
In the current study, we set out to develop a set of synthetic cfDNA quality control materials (SCQCMs) that comprises spike-in cfDNA based on micrococcal nuclease (MNase) digestion and matched genomic DNA.
Synthetic Circulating Cell-free DNA as Quality Control Materials for Somatic Mutation Detection in Liquid Biopsy for Cancer
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