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Hyperimmunoglobulin E syndrome (HIES) or Job's syndrome was first described by Davis et al.

Herpes Simplex Virus and Human Papillomavirus Coinfections in Hyperimmunoglobulin E Syndrome Presenting as a Conjunctival Mass Lesion

The disease was initially referred to as Job's syndrome, with reference to Biblical Job who was "smote with boils." The autosomal dominant form is caused by mutations in the STAT3 gene which is a major signal transduction protein involved in wound healing, angiogenesis, immune pathways, and cancer [2].

Tarhan et al., "The development of pulmonary adenocarcinoma in a patient with Job's syndrome, a rare immunodeficiency condition," Tumori, vol.

Hyper IgE Syndrome and Renal Cell Carcinoma

A diagnosis of Job's Syndrome (JS) or hyper-IgE syndrome was rendered.

A new case of Job's syndrome at the clinic: a diagnostic challenge.

A twenty-three-year-old man with a chronic anterior chest wall wound, eosinophilia, and elevated IgE--Job's syndrome

RESULTS: Pyodermas clinical types (7) incidence--Of the 100 cases studied Impetigo 30% was the most commonest clinical type followed by Folliculitis (22%), Furunculosis (10%), Ecthyma (6%), Infected scabies (5%), Sycosisbarbae (5%), Erythrasma (5%), Cellulitis (3%), Infectious Eczematous Dermatitis (3%), Paronychia (3%), Carbuncle (2%), Periportis (2%), Infected wound (2%), Job's syndrome (1%), Pitted keratolysis (1%).

Bacteriological study of pyoderma

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