The cytokines detected were IFNI3, IL-10, IL-12p70, IL-13, IL-2, IL-5, IP-10, MiP-1[alpha], MiP-1[beta], IL-6, IL1-RA, GM-CSF, RANTES, IL-1[beta], Eotaxin, Basic FGF, VEGF, PDGF-[beta], MCP-1, IL-8, IL15, IL-17, G-CSF, IL-12p70,
IL17A, IL-9 and TNF-[alpha].
(2016) MCPIP1 RNase is aberrantly distributed in psoriatic epidermis and rapidly induced by
IL17A. J.
For example, the
IL17A and IL17F gene polymorphisms were not associated with the susceptibility of RA, while they were among the most important cytokines in the pathogenesis of RA.[23]
Supplementation with Microalgae Fatty Acids Increases
IL17A, IL-12, IL-4, IL-6, IL-10, and TGF-[beta] but Decreases IFN-[gamma], TNF-[alpha], and IL-5 in Diabetic Mice.
However, data on whether
IL17A is associated with severe S.
showed that
IL17A upregulated COX-2 mRNA and protein in cancer cells lines via NF-[kappa]B and ERK1/2 signalling pathways [15].
Relative mRNA levels of
IL17A, IL-23, Treg-related transcription factor FoxP3, and cytokine TGF-3 were measured by using quantitative PCR assay via the primers from Table 1.
Selected cytokines related to acute and chronic inflammation, IL6, IL12, IFN-[gamma], TNF-[alpha], IL2, IL4, IL5, IL13, IL10, TGF-[beta]11,
IL17A, and G-CSF, were investigated by RT-PCR (as above reported) and by ELISA (Multi-Analyte ELISArray kit, Qiagen, Milan, Italy) as previously described [39].
Serum levels of IL-17A were evaluated using an ELISA kit ("Thermo Fisher Scientific Human
IL17A ELISA Kit") designed to measure human IL-17A in serum.