Mentioned in

References in periodicals archive

Likewise, failures in the expression of HNF6, HNF1b or Foxf1 result in alterations in the development of the gallbladder and the common bile duct.

Biliary Tract in Trident, an Anatomical Variation Between the Cystic Duct and its Union to the Common Hepatic Duct. A Rare Case Report/ Tracto Biliar en Tridente, una Variacion Anatomica Entre el Conducto Cistico y su Union al Conducto Hepatico Comun. Un Caso Raro

Other genes associated with MODY are infrequently detected: HNF1B, IPF, NEUROD, PDX1, KLF11, CEL, PAX4, BLK, ABCC8 and KCNJ11 (3).

A Novel De Novo Missense Mutation in HNF4A Resulting in Sulfonylurea-Responsive Maturity-onset Diabetes of the Young

PNDM is a genetically heterogeneous disorder due to mutations in 23 different genes described to date: KCNJ11, ABCC8, FOXP3, GCK, PDX1, pancreas-specific transcription factor 1A (PTF1A), EIF2AK3, SLC2A2, GATA6, GATA4, SLC19A2, WFS1, NEUROD1, NEUROG3, RFX6, LRBA, NKX2-2, MNX1, IER3IP1, INS, S T A T 3 , GLIS3 and HNF1B (3,4,5,6,7,8,9).

Neonatal Diabetes: Two Cases with Isolated Pancreas Agenesis due to Homozygous PTF1A Enhancer Mutations and One with Developmental Delay, Epilepsy, and Neonatal Diabetes Syndrome due to KCNJ11 Mutation

* MODY 5 [caused by mutations in hepatocyte nuclear factor 1 homeobox B (HNF1B)] can adversely affect development of cells in the uterus, kidneys, and kidney tracts, causing diabetes, renal cysts, and gout.

Precision Medicine in Obesity and Type 2 Diabetes: The Relevance of Early-Life Exposures

Although genetic testing for UMOD, REN, and HNF1B mutations is well established, MUC1 genetic testing remains challenging [11].

Mucin-1 Gene Mutation and the Kidney: The Link between Autosomal Dominant Tubulointerstitial Kidney Disease and Focal and Segmental Glomerulosclerosis

However, so far the only example of genetic predisposition to GDM is represented by maturity onset diabetes of the young (MODY), a clinically heterogeneous autosomal dominant monogenic disease, accounting for up to 5% of diabetes and due to mutations in different genes such as HNF4A, GCK, HNF1A, IPF1, HNF1B, and NEUROD1.

Molecular Analysis of a Genetic Variants Panel Related to Nutrients and Metabolism: Association with Susceptibility to Gestational Diabetes and Cardiometabolic Risk in Affected Women

Dosage analysis of GCK, HNF4A, and HNF1B by MLPA using MRC-Holland kit P241-D1 was performed.

Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome

The Scorecard panel initially examines the gene expression of undifferentiated and EB differentiated iPSCs for certain pluripotent (CXCL5, Nanog, Pouf51, Sox2, etc.), ectodermal (DRD4, PAX3, Sox1, Wnt1, etc.), mesodermal (HAND1, ESM1, BMP2, ODAM, etc.), and endodermal (FoxA2, GATA4, HNF1B, Sox17, etc.) markers.

Preferential Lineage-Specific Differentiation of Osteoblast-Derived Induced Pluripotent Stem Cells into Osteoprogenitors

Overexpression of miR-802 in mice causes impaired glucose tolerance and attenuates insulin sensitivity by suppressing its target gene HNF1 Homeobox B (Hnf1b).

Characterization and profiling of liver microRNAs by RNA-sequencing in cattle divergently selected for residual feed intake

Early development of hyperparathyroidism due to loss of PTH transcriptional repression in patients with HNF1b mutations?

Effects of thyroid cystectomy for primary hyperparathyroidism on immune function