[2.] Zhu Z, Li G, He L, Chen S (1985) Novel
gene transfer into the fertilized eggs of goldfish (Carassius auratus L.
In virus-transduced arthritic joint homogenate, human OPG levels were maintained for at least 21 days, with the peak at 7 days following
gene transfer (Figure 1).
While
gene transfer from a trematode could benefit the lake sturgeon, the Trichomonas pathogen is more likely to have a negative effect.
Lauren McDaniel, said the
gene transfer mechanism has been observed in lab settings for decades, but until now scientists had not documented that it also exists in nature and that it plays an important role in helping bacteria adapt.
"While lateral
gene transfer from a trematode worm could ultimately benefit the lake sturgeon, evidence of the Trichomonas pathogen is more likely to have a negative effect."
Now the
gene transfer technique is being tested for safety in people in a phase 1 clinical research study conducted by the University of Pennsylvania and the UF with support from the National Eye Institute (NEI) of the National Institutes of Health.
(Ibaraki, Japan) has patented a method for highly efficient
gene transfer into primate-derived embryonic stem (ES) cells has successfully been achieved by using a simian immunodeficiency virus vector (SIV) pseudotyped with VSV-G protein, which is a surface glycoprotein of vesicular stomatitis virus (VSV) The present invention provides simian immunodeficiency virus vectors for
gene transfer to primate ES cells.
ARGs are rapidly spread by horizontal
gene transfer among bacteria.
This exchange of genetic material, called horizontal
gene transfer, passes genes that encode the enzymes necessary for the metabolism of compounds from a donor bacterium to a recipient bacterium with a different genetic background.
In the paper, "hMaxi-K
Gene Transfer in Males with Erectile Dysfunction: Results of the First Human Trial," the authors describe the trial in which 11 patients received a single injection of different doses of hMaxi-K, a gene therapy formulation containing the human gene hSlo packaged in a "naked" DNA plasmid delivery vector.
More than fifteen years ago, the first experiments with
gene transfer in human somatic cells inspired similar hopes and fears.