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Expression levels of Enpp1, Gck, Pck1, Fas, Igfbp-1, and Apoe transcripts in the liver of rats in the cycle of fasting and refeeding.

The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone

The igfbp-1 and gck gene expressions are regulated by nutritional status or the glucose levels.

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

For TPACK-G (See Table 2), two statistically significant differences identified were GK (F = 11.97, p < .001) and GCK (F = 3.18, p < .05).

Surveying in-service teachers' beliefs about game-based learning and perceptions of technological pedagogical and content knowledge of games

The individuals with autosomal dominant mutations in GCK gene on chromosome 7p originally displayed an abnormal glucose sensing with stable mild hyperglycemia in maturity onset diabetes of the young T2DM (MODY) [75,76], which occurs at an age onset of 25 years or younger [77,78].

Apoptosis in pancreatic [beta]-islet cells in Type 2 diabetes

We also consistently observed markedly decreased expression and activity of Pepck, Gck, G6pase, and Glut2, all enzymes that control gluconeogenic flux in the liver of TCDF-treated mice.

Persistent organic pollutants modify gut microbiota-host metabolic homeostasis in mice through aryl hydrocarbon receptor activation

Despite a median 48.6 years of follow-up of 99 patients with GCK MODY, also known as MODY 2, the prevalence and severity of retinopathy, nephropathy, peripheral neuropathy, cardiovascular disease, and peripheral vascular disease weren't significantly different from those of controls (JAMA 2014;311:279-86).

Getting a grip on glucokinase MODY

And we think that if they do, it might be because they later go on to develop type 2 diabetes; for instance, if they become obese and have a genetic predisposition in addition to having their GCK mutation," Dr.

Getting a grip on glucokinase MODY management

[9.] YC Chan, HT Fung, CK Lee, SH Tsui, HK Ngan, MY Sy ML Tse, CW Kam, GCK Wong, HK Tong, ACH Lit, TW Wong, FL Lau.

Clinical study of acute poisoning: A retrospective study

Berberine regulated Gck, G6pc, Pck1 and Srebp1c expression and activated AMP-activated protein kinase in primary rat hepatCytes.

Berberine-Induced Amelioration of the Pathological Changes in Nutrients Homeostasis During Murine Intestinal Eimeria papillata Infection

Glycogen use and release are dependent on 6-phosphoric acid enzymatic synthesis and hydrolysis, and these reactions are catalysed by glucokinase (GCK) andglucose-6-phosphatase (G6Pase).

In vivo hypoglycaemic effect and inhibitory mechanism of the branch bark extract of the mulberry on STZ-induced diabetic mice

The eGFRs by GCK and GCKR genotypes were substantially in the same trend to this analysis, with the marginally significant decreasing effect of PPARD T-842CT/C + C/C on eGFR, suggesting the influence of GCK and GCKR polymorphisms on human renal functions (Table 3).

Polymorphisms in PPAR genes (PPARD, PPARG, and PPARGC1A) and the risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC study